Bencao, a general term for Chinese medicinal products, also refers to books that record Chinese medicinal products. In our 6-hour course, we will start with the introduction of representative books (Bencao) in the history of Chinese Materia Medica (CMM) development and its historical contributions. Since quality evaluation plays a vital role in ensuring the safety and effectiveness of CMM, the evolution of quality evaluation of CMM and the strategies to deal with the difficult tasks in quality control of CMM will also be included. Furthermore, an overview of US Pharmacopoeia and American Herbal Pharmacopoeia, the Hong Kong Chinese Materia Medica Standards and related applications will be introduced to help learners understand the development trends of CMM and herbal medicine in the quality standardization process. The aims of this course are to provide general information about CMM evaluation strategies to ensure the safety and quality of CMM in the protection of public health.